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  Encyclopedia of Keywords > Cell Cycle > Mitosis > Cell Cycle   Michael Charnine

Keywords and Sections
DIFFERENT CELL TYPES
PARCELLATION
CULTURE CELLS
LELAND HARTWELL
CELL CYCLE CONTROL
STAGE
INTERESTING
THOUGHT
PERIOD
ASSOCIATED
IMPORTANT
BACTERIUM
ENZYMES
GENES
GROWTH
TAMOXIFEN
STAGES
EMBRYOGENESIS
FUNCTION
REPLICATION
PHOSPHORYLATION
CELL WALL
CELL TYPES
YEAST CELLS
EUKARYOTIC CELLS
HUMANS
CELL
DAUGHTER CELLS
DIFFERENT PHASES
CAULOBACTER CRESCENTUS
ACTIVATION
CELL CYCLE ARREST
ARREST
REGULATORS
DNA REPLICATION
REGULATION
CYTOKINESIS
PHASES
PHASE
KINASE
KINASES
CYCLE
MEIOSIS
PROTEINS
CHROMATIN
DNA
Review of Short Phrases and Links

    This Review contains major "Cell Cycle"- related terms, short phrases and links grouped together in the form of Encyclopedia article.

Different Cell Types

  1. In different cell types the cell cycle can last from hours to years.

Parcellation

  1. Dehay C, Giroud P, Berland M, Smart I, Kennedy H (1993) Modulation of the cell cycle contributes to the parcellation of the primate visual cortex.

Culture Cells

  1. In human tissue culture cells, the two condensin complexes are regulated differently during the cell cycle.

Leland Hartwell

  1. Leland Hartwell, PhD Discovered key regulators of the cell cycle.

Cell Cycle Control

  1. Weinberg, R. A. (1995). The retinoblastoma protein and cell cycle control.

Stage

  1. Mitosis is a stage in the cell cycle, the sequence of events cells undergo as they grow and divide.

Interesting

  1. This is particularly interesting in that the cell cycle in A. nidulans is about 100 min (112) and conidiophores contain dozens of nuclei.

Thought

  1. Cisplatin is thought to kill cells primarily by forming DNA adducts, causing G 2 arrest in the cell cycle, triggering apoptosis (27).

Period

  1. This occurs during the middle of interphase, the period that precedes the mitotic phase in the cell cycle where preparation for mitosis occurs.

Associated

  1. Here, we report that Notch-mediated cell cycle arrest is associated with downregulation of MCM2 and MCM6 in endothelial cells and human fibroblasts.

Important

  1. In addition to cell cycle control, ribonucleotide reductase can be regulated by an S-phase independent mechanism that is important for DNA repair (9).

Bacterium

  1. Based on experimental evidence, the 'CtrA - bistable' switch mechanism [1] is proposed for cell cycle control in this bacterium [1].

Enzymes

  1. These enzymes are cell cycle regulated and focally enriched at pericentric and telomeric heterochromatin in both parasites.
  2. We are currently working with enzymes that are highly interesting for medicine because they are essential for HIV infectivity or cell cycle control.

Genes

  1. The majority of brain tumors have abnormalities of genes involved in cell cycle control, causing uncontrolled cell growth.

Growth

  1. Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion.
  2. A stage of growth in the cell cycle in which metabolism occurs without visible evidence of nuclear division.

Tamoxifen

  1. Indole-3-carbinol and tamoxifen cooperate to arrest the cell cycle of MCF-7 human breast cancer cells.

Stages

  1. In a single-cell organism, one might compare stages of the cell cycle, along with various stress conditions (heat shock, starvation, etc.).

Embryogenesis

  1. This is associated with alterations to the cell cycle in endosperm, a nutritive tissue that supports embryogenesis and seed germination.

Function

  1. As a test of the use of an oRB, we characterised a series of well-known chromatin proteins whose function is regulated during the cell cycle.

Replication

  1. To ensure the high-fidelity completion of replication, cells engage critical mechanisms that include cell cycle checkpoints and DNA repair.

Phosphorylation

  1. Suppression of phosphorylation during interphase is ensured by a labile protein, possibly a cell cycle regulated phosphatase.
  2. Human papillomavirus type 16 E6 promotes retinoblastoma protein phosphorylation and cell cycle progression.

Cell Wall

  1. The composition, properties, and form of the cell wall may change during the cell cycle and depend on growth conditions.

Cell Types

  1. Hence, repression of MCM proteins may represent a common downstream mechanism for Notch-mediated cell cycle arrest in some cell types.

Yeast Cells

  1. In yeast cells, where the nuclear envelope remains intact throughout the cell cycle, these transport regulatory mechanisms must also function during mitosis.

Eukaryotic Cells

  1. Colibactin belongs to a new family of bacterial toxins, which are able to act on the cell cycle of eukaryotic cells.

Humans

  1. The cell cycle in a simple yeast is very similar to the cell cycle in humans and is regulated by homologous proteins.
  2. Lis1 is required for nuclear migration in fungi, cell cycle progression in mammals, and the formation of a folded cerebral cortex in humans.

Cell

  1. The series of events that prepare the cell for mitosis is known as the cell cycle.
  2. In addition to possible fate determinants, centrosomes may harbor mechanisms that sense the state of the cell and regulate cell cycle progression.

Daughter Cells

  1. The cell cycle of Caulobacter showing the two daughter cells, one with a stalk and one with a flagellum, that are different in function and structure.
  2. Metaphase is a critical transition in the cell cycle because it is after this stage that chromosomes segregate to daughter cells.

Different Phases

  1. Cells in different phases of cell cycle presented both long chrysotile fibers and small fragment of fibers internalized.

Caulobacter Crescentus

  1. Fig. 1. Cell cycle of Caulobacter crescentus and cell cycle-dependent protein expression of the CtrA regulator.
  2. Caulobacter crescentus has 3,767 protein-encoding genes [ 28], of which 553 are cell cycle regulated [ 29].
  3. Skerker, J. M., and Shapiro, L. (2000). Identification and cell cycle control of a novel pilus system in Caulobacter crescentus.

Activation

  1. Entry into the cell cycle requires activation of G1 to S phase cell cycle proteins, among which retinoblastoma protein (pRb) is a key regulator.

Cell Cycle Arrest

  1. Cytomegalovirus infection induces high levels of cyclins, phosphorylated Rb, and p53, leading to cell cycle arrest.

Arrest

  1. Activation of p53 can lead to cell cycle arrest, which can be reversed under some circumstances, or apoptotic cell death.
  2. As shown on FIG. 12, the delivery of the peptides p1p27 or pRXL induced a cell cycle arrest in G1 in all tested cell lines.
  3. This is due to an impairment in dTMP synthesis which leads to cell cycle arrest in S-phase of rapidly proliferating cells, in particular hematopoietic cells.

Regulators

  1. This suggests that G1 and S phase cyclins can act as regulators of pRb function in the cell cycle by promoting pRb phosphorylation.

Dna Replication

  1. DNA replication is repressed in the motile cell until later in the cell cycle when that cell differentiates to a new stalked cell.

Regulation

  1. Minnich, S. A., and Newton, A. (1987). Promoter mapping and cell cycle regulation of flagellin gene transcription in Caulobacter crescentus.
  2. In the cervix, it is clear that both E6 and E7 crucially interfere with cell cycle regulation, and the role of E7 might be even more important.
  3. Isoforms of 14-3-3 proteins interact with diverse ligands and are involved in the regulation of mitogenesis, cell cycle progression, and apoptosis.

Cytokinesis

  1. See also: cell cycle -- cell division -- cytokinesis.

Phases

  1. Tamoxifen causes cells to remain in the G 0 and G 1 phases of the cell cycle.

Phase

  1. The G 1 phase is a period in the cell cycle during interphase, after cytokinesis and before the S phase.
  2. Interphase is a phase of the cell cycle, defined only by the absence of cell division.

Kinase

  1. Cyclin-dependent kinase is a protein kinase involved in regulation of the cell cycle.
  2. Pneumocystis has a cdc2 protein kinase, a cdc13 B-type cyclin, and a cdc25 phosphatase that participate in cell cycle regulation (6).

Kinases

  1. The cell cycle of higher eykaryotes requires the activity of a number of cyclin dependent protein kinases (CDKs).
  2. Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle.

Cycle

  1. The analyses of the cell cycle showed that blastema cells have all the characteristics of somatic cells and cycle more slowly than pluripotent stem cells.

Meiosis

  1. However, the preparatory steps that lead up to meiosis are identical in pattern and name to the interphase of the mitotic cell cycle.

Proteins

  1. Proteins are also important in cell signaling, immune responses, cell adhesion, active transport across membranes and the cell cycle.
  2. CDK drives the cell through the cell cycle by chemical modification (phosphorylation) of other proteins.
  3. They were named cyclins because the levels of these proteins vary periodically during the cell cycle.

Chromatin

  1. Constitutive heterochromatin refers to the chromatin that remains transcriptionally inert during the entire cell cycle.

Dna

  1. The structure of chromatin varies significantly between different stages of the cell cycle, according to the requirements of the DNA.
  2. The main function of the cell nucleus is to control gene expression and mediate the replication of DNA during the cell cycle.
  3. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle.

Categories

  1. Cell Cycle > Mitosis
  2. Cell Division
  3. Daughter Cells
  4. Nature > Life > Death > Apoptosis
  5. Chromatin

Subcategories

Mitosis (1)
Cytokinesis
Metaphase

    Related Keywords

      * Apoptosis * Cells
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