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  Encyclopedia of Keywords > Angiostatin > Cell Migration   Michael Charnine

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  1. Cell migration is a central process in the development and maintenance of multicellular organisms.
  2. Cell migration is a complex, tightly regulated process that involves the continuous formation and disassembly of adhesions.
  3. Cell migration is an elicited response; and, therefore, modulation of plasminogen binding to cells provides a potentially important regulatory mechanism.
  4. Cell migration is essential for proper development of numerous structures derived from embryonic neural crest cells (NCCs).

Cell Invasion

  1. The RNA-binding protein HuR promotes cell migration and cell invasion by stabilizing the beta-actin mRNA in a U-rich-element-dependent manner.

Cellular Distribution

  1. This pattern of cellular distribution may suggest a model of cell migration into the secondary lymphoid follicles.

Mutant Form

  1. Surprisingly, however, a mutant form of NEP that is inactive as a proteinase still blocks FAK phosphorylation and cell migration.

Hce Cell Migration

  1. The effects of a small interfering RNA (siRNA) specific for JNK and of a mutant form of paxillin on HCE cell migration were determined by transfection.


  1. Biochemistry of cell adhesion; the mechanism of action of Nischarin in tumor cell migration and invasion.


  1. Expression of cell adhesion molecules during initiation and cessation of neural crest cell migration.
  2. Expression of JNK siRNA or of a paxillin mutant in which Ser178 is replaced by alanine inhibited HCE cell migration during wound closure.


  1. Regulation of actin polymerization by T4 is critical to cell migration in neurons and glial cells and is important to brain development.


  1. Angiomotin regulates endothelial cell migration during embryonic angiogenesis -- Aase et al.

Tumor Cells

  1. In contrast to other cell types, LPA does not act as a mitogen, but is an efficacious stimulator of cell migration of these tumor cells.
  2. A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors.


  1. Metastasis consists of sequential steps involving cancer cell migration and invasion.
  2. CD44 may play a role in the tumor cells that progress successfully through growth and metastasis as well as cell migration.
  3. Through the process of metastasis, tumor cell migration to other areas of the body establishes neoplasms in areas away from the site of initial appearance.


  1. Tumor invasion, angiogenesis and metastasis involve secretion of proteolytic enzymes and cell migration into blood vessels.


  1. PDGF-A interactions with fibronectin reveal a critical role for heparan sulfate in directed cell migration during Xenopus gastrulation.
  2. Fibronectin plays a major role in all wound healing and promotes epithelial and endothelial cell migration within the wound site.


  1. Kirton CM, Wang T, and Dockray GJ. Regulation of parietal cell migration by gastrin in the mouse.

Endothelial Cells

  1. Expression of angiomotin in endothelial cells resulted in increased cell migration, suggesting a stimulatory role of angiomotin in cell motility.
  2. Integrins may be involved in angiogenesis as well as cell migration and the interactions between cancer and endothelial cells.
  3. The inhibition of MMPs and uPA expression in endothelial cells can lead to suppression of endothelial cell migration and invasion.


  1. Characterization of kringle domains of angiostatin as antagonists of endothelial cell migration, an important process in angiogenesis.

Cell Migration

  1. Angevine, J. and Sidman, R. 1961. Autoradiographic study of cell migration during histogenesis of cerebral cortex in the mouse.
  2. These findings indicate that angiostatin inhibits cell migration by interfering with angiomotin activity in endothelial cells.
  3. Gastrulation is a phase early in the development of animal embryos, during which the morphology of the embryo is dramatically restructured by cell migration.


  1. Angiostatin
  2. Endothelial Cells
  3. Nature > Life > Animals > Gastrulation
  4. Fibronectin
  5. Angiogenesis
  6. Books about "Cell Migration" in

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  Short phrases about "Cell Migration"
  Originally created: April 04, 2011.
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