Review of Short Phrases and Links|
This Review contains major "Chromosome"- related terms, short phrases and links grouped together in the form of Encyclopedia article.
- A chromosome is a single, long DNA strand on which thousands of genes, depending on the organism, are encoded.
- A chromosome is an organized structure consisting of DNA and histones.
- A chromosome is an organized structure of DNA and protein that is found in cells.
- A chromosome is composed mainly of DNA. Each normal cell of the human body has 23 pairs of chromosomes.
- Each chromosome is made up of DNA tightly coiled many times around proteins called histones that support its structure.
- When they were integrated with the chromosome theory of inheritance by Thomas Hunt Morgan in 1915, they became the core of classical genetics.
- Locus-specific probes hybridize to a particular region of a chromosome and are useful for detecting the location of a gene on a chromosome.
- They followed the fate of the marrow-derived cells (male) by detecting the Y chromosome.
- Ultimately, CML is diagnosed by detecting the Philadelphia chromosome.
- Bone marrow derived cells were identified by the presence of the Y chromosome, which is found only in males.
- XYY syndrome is a rare genetic disorder caused by the presence of an extra Y chromosome.
- In addition, some centers have reported that the presence of 2 copies of the ancestral HLA haplotype on chromosome 6 leads to more iron loading.
- The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16.
- WAGR Syndrome is caused by defects (mutations) of adjacent genes on a region of chromosome 11 (11p13).
- The gene for alkaptonuria has been mapped to chromosome number 3 in the region of bands 3q21- q23.
- The human D2 gene has been localized to chromosome 11.
- The human D3 gene has been localized to chromosome 3, and, like the genes for D2 receptors, D3 mRNA also occurs in longer and shorter spliced forms.
- The human D 5 gene has been localized to chromosome 4.
- Fine mapping of a human chromosome 6 ferritin heavy chain pseudogene: relevance to haemochromatosis.
- Type I also called classic hemochromatosis is due to mutations of HFE, a gene located on chromosome 6.
- In 1996, HFE, the gene for HHC, was mapped on the short arm of chromosome 6 (6p21.3).
- Most cases of transient neonatal diabetes appear to be caused by the inheritance of an extra copy of a region of chromosome 6 from the father.
- Cases with increased abnormal eosinophils in the bone marrow associated with a chromosome 16 abnormality have a favorable prognosis.
- In some cases, the chromosome is missing in some cells but not others, a condition referred to as mosaicism[ 2] or 'Turner mosaicism'.
- Review [Clinical, genetic and pathological aspects of frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17)] [Rinsho Shinkeigaku.
- Neuropathological features of frontotemporal dementia and parkinsonism linked to chromosome 17q21-22 (FTDP-17): Duke Family 1684.
- This gives us strong reasons to propose that genes along the chromosome specify the map of the cell, a kind of celluloculus.
- A "fitness function" is used to map a CHROMOSOME to a FITNESS value.
- Considering conserved synteny, we were able to map the human gene to chromosome 3q in six alkaptonuria pedigrees of Slovak origin.
- Tandem repeat sequences: Multiple copies of the same base sequence on a chromosome; used as a marker in physical mapping.
- Mapping of a susceptibility locus for Crohn's disease on chromosome 16.
- Mapping of a gene causing familial Mediterranean fever to the short arm of chromosome 16.
- In any of these cases, if that egg gets fertilized and becomes a male, the man will get that X chromosome and be color-blind.
- However, during egg and sperm formation, a mutation can develop in the I2S gene on his X chromosome.
- For example, an egg or a sperm may receive two copies of the same chromosome.
- The sperm and egg from the mother and father each contribute one copy of each chromosome.
- In the second step, the sperm and egg join to make a single cell, which restores the chromosome number.
- Males with fragile X syndrome have a defective X chromosome that produces a faulty protein that results in retarded brain development.
- Fragile X syndrome is caused by a mutated gene on the X chromosome.
- Less than 10 percent of Turner syndrome results from having the normal number of chromosomes (46 total), but missing a portion of the X chromosome.
- In Turner syndrome, cells are missing all or part of an X chromosome.
- Turner's syndrome is a genetic disorder caused by a missing X chromosome that occurs only in females.
- Chromosome walking is employed when we know the sequence but don't have a clone of a gene.
- Although emb88is located on chromosome 1, molecular analysis of genomic DNA directly adjacent to the T-DNA left border revealed sequence from chromosome 5.
- For bacteria, which usually have just one chromosome, a genome project will aim to map the sequence of that chromosome.
- Chromosome walking: A technique for cloning everything in the genome around a known piece of DNA (the starting probe).
- Chromosome 22 has a 48% GC content, whereas chromosome 21 has 41% and the average over the genome is 42%.
- The genome of Caulobacter crescentus is structured in a circular chromosome and is comprised of 4,016,942 bp encoding for 3,767 genes.
- The SBDS gene resides in a block of genomic sequence that is locally duplicated on the chromosome.
- Doctors look for chromosome changes in the cells of some leukemias.
- Leukemias with certain types of chromosome changes have a poor outlook, while those with other types of genes can have a very good outlook.
- The leukemia cells may have new chromosome changes, in addition to the Philadelphia chromosome.
- The oxidation of the drug results in the production of reactive intermediates which affect genes and may cause structural changes in the chromosome.
- The aim of this work was to isolate new DNA markers linked to the Silene latifolia Y chromosome.
- Association of parathyroid tumors in multiple endocrine neoplasia type 1 with loss of alleles on chromosome 11.
- Certain traits like colorblindness and hemophilia are on alleles carried on the X chromosome.
- Haplotype: the combination of genetic markers or alleles found along a region of a chromosome.
- For each neighboring site, we then compute its inferred FRC (8), assuming the S variant arose on a single chromosome (haplotype).
- Recently, a gene for hereditary pancreatitis, transmitted as an autosomal dominant trait with variable penetrance, has been identified on chromosome 7.
- The causative gene of hereditary pancreatitis was identified in 1996 through mutational analysis of genes within chromosome 7q35.
- The gene for antithrombin is located on chromosome 1 band q23.1-23.9, has 7 exons and 6 introns, and is 13.5 kilobases (kb) long.
- HeFH patients were found to have one copy of a mutated LDLR gene, which normally is located on chromosome 19p13 and comprises 18 exons.
- In a few cases, periventricular heterotopia has been associated with abnormalities in chromosome 5.
- A specific haplogroup R1a1 defined by the M17 (SNP marker) of the Y chromosome (see: for nomenclature) is associated by some with the Kurgan culture.
- It is associated with mutations of the ceruloplasmin (Cp) gene on chromosome 3q (3).
- Linkage map: A map of the relative positions of genetic loci on a chromosome, determined on the basis of how often the loci are inherited together.
- Haplotype A way of denoting the collective genotype of a number of closely linked loci on a chromosome.
- In the context of trisomy detection, the suspected aneuploidy region is usually the entire chromosome and N denotes the number of loci per chromosome.
- Mutations in the parkin gene (PARK2 locus, chromosome 6q) account for up to 50% of AREP families.
- BACKGROUND: AR-JP has been mapped to chromosome 6q and is caused by several mutations of the parkin gene (Park 2).
- The gene for the X-linked form of Kallmann's syndrome has been mapped to chromosome Xp22.3, 1 and several mutations have been described.
- Two genes positioned near one another on a chromosome may encode proteins that figure in the same cellular process or in completely unrelated processes.
- Transcription factors (like all proteins) are transcribed from a gene on a chromosome into RNA, and then the RNA is translated into protein.
- Chromosome: A chromosome is a thread-like structure made up of DNA and proteins.
- The TSC1 gene, discovered in 1997, is on chromosome 9 and produces a protein called hamartin.
- TSC1 is located on chromosome 9q34 and encodes for the protein hamartin.
- One important research finding was the discovery of the TSC2 gene in close proximity to the gene for polycystic kidney disease (PKD1) on chromosome 16.
- The TSC2 gene is located on chromosome 16p13.3 and codes for the 200 kDa protein tuberin containing 1807 amino acids.
- A second gene for the disease (TSC2) is located on the short arm (p) of chromosome 16 (16p13.3).
- The other gene, TSC2, is located on chromosome 16 and is called the tuberin gene.
- TSC2 is located on chromosome 16p13.3 and encodes for the protein tuberin.
- At least 200 genes exist on the location of chromosome 9, however, so the research will continue to identify the particular gene responsible for the cancer.
- There are thousands of genes on each chromosome and hundreds of nucleotides in the DNA sequence of each gene.
- The DNA sequence and analysis of human chromosome 6.
- The DNA sequence of human chromosome 22.
- TSC2 is located on chromosome 16 and encodes tuberin .
- The TSC2 gene, discovered in 1993, is on chromosome 16 and produces the protein tuberin.
- The second gene (TSC 2) maps to chromosome 16, specifically 16p13, and codes for tuberin.
- TSC1 is located on chromosome 9 and encodes a protein referred to as hamartin .
- TSC1, the abnormality is located on chromosome 9q34 and TSC2, the abnormality is located on chromosome 16p13.
- No missense mutations occur in TSC1. In TSC2, the gene abnormalities are on chromosome 16p13.
- Non-disjunction of the sex chromosome during Anaphase I of meiosis ------ Trisomy (47,XXY) Hypogonadism, tall stature, gynecomastia.
- Context: Klinefelter syndrome is characterized by hypogonadism and infertility, consequent on the presence of extra X chromosome(s).
- In Klinefelter syndrome, two or more X chromosomes are present in addition to one Y chromosome.
- Diagnosis of Klinefelter syndrome is confirmed by examining chromosomes for evidence of more than one X chromosome present in a male.
- Genetics The gene for Factor VIII is located on the X chromosome (Xq28).
- Genetics is rife with potentially confusing scientific terminology associated with chromosomes and chromosome number.
- The notion of the chromosome theory of heredity is very important to the understanding of evolution and genetics.
- The location (or locus) of a gene and the chromosome on which it is situated is in a sense arbitrary.
- One of multiple alternative forms of a single gene, each of which is a viable DNA sequence occupying a given position, or locus on a chromosome.
- Linkage of a new locus for autosomal dominant familial spastic paraplegia to chromosome 2p.
- Linkage analysis with chromosome 9 markers in hereditary essential tremor.
- Selective intestinal malabsorption of vitamin B12 displays recessive mendelian inheritance: assignment of a locus to chromosome 10 by linkage.
- A gene for limb-girdle muscular dystrophy maps to chromosome 15 by linkage.
- Linkage to chromosome 1q has been established recently, but the gene remains unknown.
- The chromosome 1 of assam macaque is a pericentric inversion of human chromosome.
- Locus: 6p21.3 The HFE gene is found in region 21.3 on the short (p) arm of human chromosome 6.
- It is caused by mutations in the Werner syndrome gene (WRN), which resides on the short arm of human chromosome 8.
- It is an autosomal recessive disorder linked to a mutation of the HFE gene on the short arm of chromosome 6.
- Microsatellite analysis showed no linkage of the hemochromatosis phenotype with the short arm of chromosome 6, the site of the HFE gene.
- Hereditary haemochromatosis is an autosomal-dominant disorder with variable penetrance, and results from a mutation of the HFE gene located on chromosome 6.
- Identification and characterization of the tuberous sclerosis gene on chromosome 16.
- Research of families with hereditary pancreatitis has led to the identification of several mutations in the cationic trypsinogen gene on chromosome 7.
- Identification and regional localization of DNA markers on chromosome 7 for the cloning of the cystic fibrosis gene.
- Encyclopedia of Keywords > Nature > Life > Gene
- Science > Biology > Genetics > Dna
* Chromosome 15
* Chromosome 17
* Chromosome 22
* Chromosome Abnormality
* Chromosome Walking
* Cri Du Chat
* Cri Du Chat Syndrome
* Extra Chromosome
* Genetic Disorder
* Genetic Disorders
* Genetic Linkage
* Long Arm
* Philadelphia Chromosome
* Short Arm
* Tau Gene
* Trisomy 21
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