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Anaesthetic Drugs

  1. It has the most rapid onset and offset of the volatile anaesthetic drugs used for general anaesthesia due to its low solubility in blood.
  2. There are 2 classes of local anaesthetic drugs defined by the nature of the carbonyl-containing linkage group.
  3. Anaesthetic drugs: linking molecular actions to clinical effects.


  1. Pharmacognosy is the oldest discipline on pharmaceutical.
  2. Pharmacognosy is the study of medicines from natural sources.
  3. Pharmacognosy is a term derived from the Greek word 'gnosis' which means knowledge.


  1. The effects of the ampakine in neocortex tended to be greater in the deeper than superficial layers but this did not reach statistical significance.
  2. When drugged rats were treated with the AMPAKINE , the respiratory distress quickly resolved.
  3. But with an ampakine, maybe you could hit a curveball.--- Also intriguing to Lynch is the effect of ampakines on memory.


  1. Pharmaceutics : The science of dosage form design.
  2. Pharmaceutics and industrial pharmacy which concerns on how to convert medication and drugs to suitable drug dosage forms.
  3. This program emphasizes not only pharmaceutics and pharmacodynamics but also cellular and molecular biology as applied to pharmacogenomics and toxicology.

Pharmacy Practice

  1. Dr Klepser is a pharmacy practice professor at Ferris State University.
  2. Your final year will consist of practicums with pharmacy practice faculty and licensed preceptors at their practice sites.
  3. Completion of pharmacy practice residency or equivalent experience.


  1. Midazolam is a benzodiazepine commonly used in the ED to provide sedation.
  2. Midazolam is a short-acting benzodiazepine central nervous system (CNS) depressant.
  3. Midazolam was actively self-administered in primate models used to assess the positive reinforcing effects of psychoactive drugs.
  4. Midazolam is a safe drug, because it does not have any active metabolites.
  5. Midazolam is a benzodiazepine in the same family as diazepam.


  1. Doxazosin is an alpha-adrenergic blocking agent used to treat hypertension and benign prostatic hyperplasia.
  2. Doxazosin is a quinazoline compound that is a selective inhibitor of the alpha1 subtype of alpha adrenergic receptors.
  3. Doxazosin is a vasodilator which causes a fall in arterial pressure.
  4. Doxazosin was administered at the same time as tadalafil or placebo after a minimum of seven days of doxazosin dosing.
  5. Doxazosin was not clastogenic in the in vivo mouse micronucleus assay.


  1. Estazolam is a benzodiazepine used to treat sleep disorders.
  2. Estazolam is used as a hypnotic for the short-term treatment of patients with insomnia.
  3. Estazolam is used on a short-term basis to help you fall asleep and stay asleep through the night.
  4. Estazolam was clinically effective in 94% of patients, no patient needing either additional drugs for sedation or heavy restraint.
  5. Estazolam is a new benzodiazepine hypnotic agent with an intermediate half-life of 12 to 15 hours.


  1. Eszopiclone is the first of several new agents entering the US market for the treatment of insomnia.
  2. Eszopiclone is the first nonbenzodiazepine sleep aid that is not limited to short-term use.
  3. Eszopiclone is a cyclopyrrolone derivative and an enantiomer of zopiclone, a sedative hypnotic not marketed in the United States.
  4. Eszopiclone is a cytochrome P450 3A4 substrate; thus, both inhibitors and inducers of 3A4 affect therapeutic concentrations.
  5. Eszopiclone is a white to light-yellow crystalline solid.


  1. Etoricoxib is a potent selective COX-2 inhibitor in man.
  2. Etoricoxib is a second-generation cyclo-oxygenase (COX)-2-selective inhibitor.
  3. Etoricoxib is a white to off-white powder.
  4. Etoricoxib is an oral, selective cyclo-oxygenase 2 (COX 2) inhibitor within the clinical dose range.
  5. Etoricoxib was comparable in efficacy to indomethacin at a dosage of 50 mg 3 times daily, and it was generally safe and well tolerated.


  1. Felbamate was the first new antiepileptic drug to gain FDA approval (in 1993) and its introduction was met with much enthusiasm and initial success.
  2. Felbamate was approved for use in the United States in 1993.
  3. Felbamate is a low-extraction drug and is metabolized mainly by hydroxylation and conjugation.
  4. Felbamate is a potent anticonvulsant, very effective against multiple seizure types.
  5. Felbamate is a weak inhibitor of CYP2C19 and a weak inducer of CYP3A4, which complicates its use and causes drug interactions with other AEDs.


  1. Fosphenytoin is for parenteral use only.
  2. Fosphenytoin was developed to eliminate the poor aqueous solubility and irritant properties of intravenous phenytoin.
  3. Fosphenytoin is a better IV preparation than PHT, mainly because of tolerability and safety.
  4. Fosphenytoin is a diphosphate ester of phenytoin that is very water-soluble, making it a convenient intravenous dosage form.
  5. Fosphenytoin is a new phenytoin prodrug that fulfills many of the properties of an ideal anticonvulsant drug.


  1. Levetiracetam is a new anticonvulsant for adjunctive treatment of partial epilepsy.
  2. Levetiracetam is a new anti-epileptic drug that is currently not licensed for use in children.
  3. Levetiracetam is a highly soluble and permeable compound.
  4. Levetiracetam is a new anti-convulsant with impressive pivotal trial credentials.
  5. Levetiracetam is a novel anti-epileptic drug with broad?@spectrum activity in several animal models mimicking both partial and generalized epilepsy.


  1. Metronidazole is an antibiotic used tofight anaerobic bacteria and parasites like giardia.
  2. Metronidazole is a nitroimidazole and should be used with care in patients with evidence of or history of blood dyscrasia.
  3. Metronidazole is a first generation nitroimidazole and tinidazole is a second generation nitroimidazole.
  4. Metronidazole is a member of the imidazole class of antibacterial agents and is classified therapeutically as an antiprotozoal and antibacterial agent.
  5. Metronidazole is a nitroimidazole and should be used with caution in patients with evidence of or history of blood dyscrasia.


  1. Nortriptyline was approved as an antidepressant by the FDA in 1964.
  2. Nortriptyline is used to treat depression and for the management of chronic, severe neurogenic pain.
  3. Nortriptyline is used to relieve symptoms of depression.
  4. Nortriptyline is also a sedative and is useful in depressed patients with insomnia, restlessness, and nervousness.
  5. Nortriptyline is a second generation tricyclic antidepressant marketed as the hydrochloride under the trade names Aventyl --, Pamelor -- and Nortrilen --.


  1. Risedronate was evaluated in two one-year studies14,15 for the prevention and treatment of glucocorticoid-induced osteoporosis.
  2. Risedronate is a bisphosphonate that acts primarily to inhibit bone resorption.
  3. Risedronate is a bisphosphonate that, like other bisphosphonates, inhibits osteoclast activity and reduces bone resorption.
  4. Risedronate is a first-generation bisphosphonate.
  5. Risedronate is a member of the new class of pyridinyl bisphosphonates.


  1. Teicoplanin is a bactericidal, glycopeptide antibiotic produced by fermentation of Actinoplanes teichomyceticus.
  2. Teicoplanin is a complex mixture of closely related compounds that share certain structural and antimicrobial properties with vancomycin.
  3. Teicoplanin is a glycopeptide antibiotic complex produced by Actinoplanes teichomyceticus structurally related to Catalog TCP. Product Name Teicoplanin.
  4. Teicoplanin is a glycopeptide antibiotic, similar in spectrum to vancomycin.
  5. Teicoplanin is a less toxic replacement for vancomycin in most situations where resistant organisms are encountered.


  1. Tinidazole is a synthetic antiprotozoal agent.
  2. Tinidazole is a nitroimidazole and should be used with caution in patients with evidence of or history of blood dyscrasia.
  3. Tinidazole is similar to metronidazole with a longer duration of action; it causes less gastro-intestinal disturbance but costs more.
  4. Tinidazole is the major drug-related constituent in plasma after human treatment, along with a small amount of the 2-hydroxymethyl metabolite.
  5. Tinidazole was also mutagenic in a tester strain of Klebsiella pneumonia .

Tylenol Pm

  1. Recently, a Tylenol PM ad in three women's magazines suggested that the pill could help prevent acne and dry skin.
  2. Diphenhydramine, an ethanolamine-class antihistamine, is found in most OTC sleep aids and allergy preparations, such as Tylenol PM and Benadryl.
  3. Law enforcement says youths now are mixing heroin with other over-the-counter nighttime cold medicines with diphenhydramine, instead of just Tylenol PM.


  1. Vinorelbine is a moderate vesicant.
  2. Vinorelbine is a chemotherapy drug that can be used to treat breast cancer.
  3. Vinorelbine is a drug used to treat certain types of lung cancer.
  4. Vinorelbine is a semi-synthetic vinca alkaloid that binds to specific sites on tubulin and prevents their polymerization and assembly.
  5. Vinorelbine is a semisynthetic derivative of vinblastine, a naturally occurring compound that is extracted from periwinkle plants.


  1. ZONISAMIDE is a medicine to treat partial seizures in adults.
  2. Zonisamide is an antiseizure drug chemically classified as a sulfonamide and unrelated to other antiseizure agents.
  3. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies.
  4. Zonisamide was approved for use in the United States in 2000.
  5. Zonisamide was as effective as carbamazepine and valproic acid in monotherapy trials.


  1. Acebutolol is a beta blocker.
  2. Acebutolol is a cardioselective beta blocker with ISA (Intrinsic Sympathomimetic Activity, see article on Pindolol).


  1. Aceclidine is a cholinomimetic obtained by chemical synthesis, used in the form of ophthalmic solution in the treatment of glaucoma.
  2. Aceclidine acts primarily on the muscarinic receptor.
  3. Side effects of aceclidine include increased salivation, bradycardia (in excessive doses).


  1. Acetohexamide is a sulfonylurea medication used to treat diabetes mellitus type 2, particularly in people whose diabetes cannot be controlled by diet alone.
  2. Acetohexamide lowers blood sugar by stimulating the pancreas to secrete insulin and helping the body use insulin efficiently.
  3. For this reason, acetohexamide is not used to treat Diabetes mellitus type 1.


  1. Acidifier: An herb or substance that increases or imparts acidity, or lessens alkalinity, to the body fluids, especially the blood or the urine.
  2. Because ammonium chloride is not always available from hospital pharmacies, ascorbic acid may be the only other urine acidifier available.


  1. Acriflavine is a topical antiseptic.
  2. Acriflavine is also used as treatment for external fungal infections of aquarium fish.
  3. Acriflavine was developed in 1912 by Paul Ehrlich, a German medical researcher and was used during the First World War against sleeping sickness.


  1. Actinomycin D blocks double-stranded DNA - dependent DNA synthesis, but not RNA-dependent DNA synthesis.
  2. Therefore, in the presence of Actinomycin D the reverse transcriptase reaction itself will be measured only.
  3. Actinomycin D is used in combination with primary surgery, radiotherapy, and other drugs, particularly vincristine and cyclophosphamide.

Active Ingredient

  1. It turns out that the active ingredient in this herb, Forskolin, is capable of beneficial action against a wide range of conditions.
  2. The active ingredient in BARACLUDE is entecavir.
  3. Name: State the brand name and manufacturer of the product, not just the active ingredient.

Adverse Event

  1. Only four percent of the 47 patients enrolled experienced a significant adverse event at 30 days.
  2. The most common (---5%) treatment-related adverse event was unpleasant taste (eszopiclone 1 mg, 8.3%; eszopiclone 2 mg, 11.4%;placebo, 15.0%).
  3. Thirty three percent of the diltiazem treated patients had one or more adverse event compared to 18% in the placebo group.


  1. Commonly used decongestants include oxymetazoline (Afrin and other brands) and pseudoephedrine (Sudafed, Actifed, and other brands).
  2. A final precaution about nasal decongestants involves continued inappropriate use of nasal sprays or drops (eg, Afrin, Neo-Synephrine).
  3. Nasal decongestants include phenylephrine (Neo-Synephrine) and oxymetazoline (Afrin).


  1. Alamethicin is a peptide.
  2. Alamethicin is a well-studied channel-forming peptide that has a prototypical amphipathic helix structure.
  3. In this model alamethicin helices associate to form a bundle with a central lumen, like a barrel made of helical peptides as staves (Fig.


  1. Albendazole is a white to off-white powder.
  2. Albendazole is an effective treatment for some forms of microsporidiosis.


  1. Alfuzosin is a functionally uroselective alpha-blocker, therefore, having minimal effects on the cardiovascular system.
  2. Alfuzosin is a selective alpha 1 adrenoreceptor antagonist that has efficacy and safety profiles similar to tamsulosin (Flomax, Boehringer Ingelheim).
  3. Alfuzosin is an alpha-adrenergic blocking agent used to treat hypertension and benign prostatic hyperplasia.

Alkylating Agent

  1. It is a nitrogen mustard alkylating agent and can be given orally.
  2. Busulfan is a chemotherapy drug that is an alkylating agent (slows the growth of cancer cells).
  3. MYLERAN (busulfan) is a bifunctional alkylating agent.


  1. Allopurinol is a white, powdery drug used to treat chronic gout.
  2. Allopurinol is a structural analogous of hypoxanthine, inhibitor of xanthine oxidase, the last enzyme involved in uric acid synthesis pathway.
  3. Allopurinol is a structural analogue of the natural purine base, hypoxanthine.
  4. Allopurinol is a white, powdery drug used to treat gout.
  5. Allopurinol is an analog of the natural purines in the body, and is quickly metabolised to oxipurinol which is also a xanthine oxidase inhibitor.

Alpha Hydroxy Acid

  1. An alpha hydroxy acid that may be less irritating than glycolic acid and lactic acid.
  2. Our 8% Alpha Hydroxy Acid Solution has a pH of 3.5, and our Skin Revealing Body Lotion with 10% AHA has a pH of 3.
  3. EXFOLIATING: Use a 1% to 2% beta hydroxy acid (BHA) product (or an 8% alpha hydroxy acid (AHA) product) to exfoliate the skin.

Alpha Blocker

  1. Bryan College Station Eagle, I often prescribe an alpha blocker, such as tamsulosin (Flomax) or alfuzosin (Uroxatral), to treat benign prostatic hyperplasia.
  2. This medicine is an alpha blocker used to treat symptoms of benign prostatic hypertrophy (bph).
  3. Phenoxybenzamine is a non-specific, irreversible alpha blocker used in the treatment of hypertension, and specifically that caused by pheochromocytoma.


  1. Amidrine, Duradrin, or Midrin, is a combination of Acetaminophen, Dichloralphenazone, and Isometheptene used mostly to treat headaches.
  2. Where to buy prescription drugs and Amidrine and learn information about medication.
  3. Amidrine Overview: Common Use(s) Amidrine is most commonly used to treat migraines (or tensioned-type headaches).


  1. Amiloride is a pyrazine ring compound clinically used in humans as a diuretic.
  2. Amiloride is a weak diuretic when administered alone and is presently used only in combination with HCTZ for its potassium sparing properties.
  3. Amiloride is one of the prescription medications your Dr. might prescribe to help you keep your potassium level up.
  4. Amiloride is used in conjunction with DIURETICS to spare POTASSIUM loss.

Aminocaproic Acid

  1. Aminocaproic acid is used to treat excessive postoperative bleeding.
  2. The patient received 2 g of aminocaproic acid every 6 hours for a total dose of 26 g.
  3. Aminocaproic acid must not be used in the presence of DIC without concomitant heparin.


  1. Example inducers include aminoglutethimide, carbamazepine, phenobarbital, and rifampin.
  2. Aminoglutethimide Increases theophylline clearance by 25% decrease induction of microsomal enzyme activity.


  1. Example substrates include aminophylline, fluvoxamine, mexiletine, mirtazapine, ropinirole, theophylline, and trifluoperazine.
  2. It should also be noted that doxapram cannot be given in the same infusion line as aminophylline as the two are incompatible.
  3. In such patients skin patch tests are positive for ethylenediamine, a component of aminophylline, and negative for theophylline.

Aminosalicylic Acid

  1. Aminosalicylic acid is an antibiotic used to treat tuberculosis.
  2. Aminosalicylic acid was introduced to clinical use in 1948.


  1. Amlodipine is a calcium ion influx inhibitor (calcium entry blocker or calcium ion antagonist).
  2. Amlodipine is a member of the dihydropyridine class of calcium antagonists.
  3. Amlodipine is an effective treatment of hypertension in once-daily doses of 2.5-10 mg while benazepril is effective in doses of 10-80 mg.
  4. Amlodipine is one of a series of dihydropyridine calcium antagonists.


  1. Anagrelide is a quinazolin derivative that is both a platelet-lowering agent and an inhibitor of platelet aggregation.
  2. Anagrelide is a specific inhibitor of the c-mpl receptor of thrombopoetin.
  3. Anagrelide is an inhibitor of cyclic AMP phosphodiesterase III.

Angiogenesis Inhibitor

  1. Phase I trial of the angiogenesis inhibitor TNP-470 for progressive androgen-independent prostate cancer.
  2. Phase I dose-escalating trial of SU5416, a novel angiogenesis inhibitor in patients with advanced malignancies.
  3. SU6668 is a potent, broad spectrum angiogenesis inhibitor that exhibits antitumor properties.


  1. Anidulafungin is an echinocandin, a class of antifungal drugs that inhibits the synthesis of 1,3----D-glucan, an essential component of fungal cell walls.
  2. Anidulafungin is a novel antifungal agent of the echinocandin class that is intended for the treatment of invasive fungal disease.
  3. Anidulafungin is a semi-synthetic echinocandin with antifungal activity.
  4. Anidulafungin is a semi-synthetic lipopeptide that belongs to the echinocandin class of antifungal agents.
  5. Anidulafungin is a semisynthetic echinocandin, and voriconazole is an extended-spectrum triazole.


  1. Nature > Chemistry > Biochemistry > Pharmacology
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Related Keywords

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